by Nicole M. Chapman, Hongbo Chi
Metabolic rewiring of immune cells has broad impacts on immune responses and disease outcomes. Systems biology approaches, such as multi-omics profiling and perturbation screening, could uncover new actionable targets and therapeutic avenues to explore.
Metabolic regulation of immune function is a complex and dynamic process. This Perspective highlights how systems biology approaches, including multi-omics profiling and perturbomics screening, are being used to unravel this complexity and advance understanding of immunometabolism.
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